Osteocalcin (OC), also known as the bone Gla protein (BGP), is a 5.8 kDa, hydroxyapatite-binding protein that could be synthesized by osteoblasts, odontoblasts and hypertrophic chondrocytes and is the most abundant non-collagenous protein found in bone matrix. Early identification and effective therapeutic monitoring to PMO is necessary to reduce the public health burden of this pervasive disease. PMO may lead to fragility fracture and is one of the most disabling consequences of postmenopausal women. Postmenopausal osteoporosis (PMO) results from estrogen deficiency after menopause and is a major type of primary osteoporosis. The osteoporotic bone is fragile and susceptible to fracture. Osteoporosis (OP) is a systemic skeletal disorder characterized by low bone mass and deteriorated microarchitecture of bone tissue.
#7.18 META UPDATE#
More trials with standardized methodologies for the evaluation of circulatory OC are awaited to update our current findings. Therefore, sOC is currently not a good indicator for the high bone turnover status in PMO. OC molecules are quite heterogeneous in the circulation and can be influenced by glucose metabolism. Our analysis revealed no significant difference in sOC level between PMO cases and controls according to all the current eligible studies. For different regions, no significant difference in sOC was found in Asian population between cases and controls, while the pooled sOC level was significantly higher in European PMO cases than controls. Subgroup analysis also revealed no significant difference in intact OC or N-terminal mid-fragment of the OC molecule between groups. We found no significant difference in the pooled sOC level between PMO patients and controls. Ten case-control studies with 1577 postmenopausal women were included in this meta analysis. Subgroup analysis according to potential confounding factors (different OC molecules and regions of the study population) was also performed. A meta-analysis of case-control studies was performed to compare the pooled sOC level between PMO patients and postmenopausal controls. We searched the online database of PubMed and Cochrane Library. However, the change of serum OC (sOC) level in PMO cases compared to postmenopausal controls remains controversial. MetaLabelCtrl.Text = String.Circulatory osteocalcin (OC) has been widely used as a biomarker to indicate bone turnover status in postmenopausal osteoporosis (PMO). RequiredFieldValidator1.Enabled = !MetaField.AllowNulls / Binds a data source to the invoked server control and all its child controls. Protected void Page_Load(object sender, System.EventArgs e) / The instance containing the event data. / Handles the Load event of the Page control.
#7.18 META CODE#
The code behind simlar to public partial class M圜ontrol : CoreBaseUserControl, IMetaControl for just purchase order or field8.ascx for all classes In "~/Apps/Core/MetaData/Controls/" place a file called
If you want to create the control do this Yes change the type or create the control. Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint) +3178 (MetaClass metaClass, Dictionary`2 metaObjects, String defaultLanguage) +723 TemplateControl.LoadControl(VirtualPath virtualPath) +164 GetVPathBuildResult(HttpContext context, VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile, Boolean ensureIsUpToDate) +192 GetVPathBuildResultWithNoAssert(HttpContext context, VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile, Boolean throwIfNotFound, Boolean ensureIsUpToDate) +203 GetVPathBuildResultInternal(VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile, Boolean throwIfNotFound, Boolean ensureIsUpToDate) +12327668
Information regarding the origin and location of the exception can be identified using the exception stack trace below. Please review the stack trace for more information about the error and where it originated in the code.Įxception Details: : The file '/Apps/Core/MetaData/Controls/.ascx' does not exist.Īn unhandled exception was generated during the execution of the current web request. The file '/Apps/Core/MetaData/Controls/.ascx' does not exist.ĭescription: An unhandled exception occurred during the execution of the current web request.
#7.18 META INSTALL#
We have verified against the default install of commerce manager and our appsettings and so on is the same as on a fresh install of commerce manager. We are receiving a YSOD when trying to edit a purchase order in commerce manager.
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